Fig. 5

miRNA-4701-5p reduced the apoptosis of IL-1β induced CHON-001 cells by downregulating HMGA1. A, B Flow cytometry analysis of apoptotic cell. C, D Detection of cleaved-caspase3 expression and cleaved-caspase3/GAPDH ratio using western blot assay. **p < 0.01 versus control; ##p < 0.01 versus IL-1β + mimic control; &&p < 0.01 versus IL-1β + miRNA-4701-5p mimic + control-plasmid