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Fig. 4 | Journal of Orthopaedic Surgery and Research

Fig. 4

From: Inhibition of cc chemokine receptor 10 ameliorates osteoarthritis via inhibition of the phosphoinositide-3-kinase/Akt/mammalian target of rapamycin pathway

Fig. 4

Effects of CCR10-siRNA on the PI3K/Akt/mTOR pathway in CHON-001 cells. The CHON-001 cells were divided into four groups: Control, IL-1β, IL-1β + control-siRNA, or IL-1β + CCR10-siRNA group. (A) The expression levels of p-PI3K, p-Akt, and p-mTOR were determined using Western blotting. (B-D) The p-PI3K/PI3K, p-Akt/Akt, and p-mTOR/mTOR ratios were quantified. **P < 0.01

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X