A meta-analysis of randomized controlled trials: evaluating the efficacy of isokinetic muscle strengthening training in improving knee osteoarthritis outcomes

Table 6 Sensitivity analysis: different outcome indicators

Outcome indicators		Excluded articles	I² before excluding article (%)	I² after excluding article (%)	P-value before excluding the article	P-value after excluding the article
60°/ second	Flex PT	Hai Wang et al., 2013 [44]	99	97	= 0.0001	< 0.00001
60°/ second	Ext PT	Hai Wang et al., 2013 [44]	97	90	< 0.00001	< 0.00001
180°/ second	Flex PT	Hai Wang et al., 2013 [44]	97	67	= 0.008	< 0.00001
180°/ second	Ext PT	Hai Wang et al., 2013 [44]	97	76	= 0.007	< 0.0001
Flex TW		Wei Chen et al., 2022b [67]	78	21	< 0.00001	< 0.00001
Ext TW		Su-Hua Shi et al., 2014 [46]	56	41	< 0.00001	< 0.00001
Flex MRTW		Jie Zhang, 2019a [57]	89	76	= 0.003	= 0.003
Ext MRTW		Jie Zhang, 2019a [57]	77	70	< 0.00001	< 0.0001
Flex AP		Hai Wang et al., 2013 [44]	99	88	= 0.03	= 0.0001
Ext AP		Hai Wang et al., 2013 [44]	82	59	= 0.0003	< 0.0001
VAS scores		Xiao-Jie Yu et al., 2007a [40]	89	87	< 0.00001	< 0.00001
LI scores		Mao-Hsiung Huang, 2003c [37]	74	38	< 0.00001	< 0.00001
WOMAC scores		Jie Zhang, 2019a [57]	93	84	= 0.006	= 0.005
LKSS scores		Xia He et al., 2018 [52]	93	74	< 0.00001	< 0.00001
Flex ROM of the knee joint		Min Rang, 2022 [66]	65	0	< 0.00001	< 0.00001
Ext ROM of the knee joint		Min Rang, 2022 [66]	96	57	= 0.93	= 0.07
6MWT		Xia He et al., 2018 [52]	79	9	= 0.68	= 0.51

Flex/Ext PT Knee flexors/extensors peak torque, Flex/Ext TW Knee flexors/extensors total work, Flex/Ext MRTW Knee flexors/extensors max rep total work, Flex/Ext AP Knee flexors/extensors average power VAS Visual Analog Scale, LI Lequesne index, WOMAC Western Ontario and McMaster University Osteoarthritis Index, LKSS Lysholm Knee Scoring Scale, ROM Range of motion, 6MWT 6-min walk test

ISSN: 1749-799X