Fig. 1
From: Effects of traditional Chinese medicine Zuo-Gui-Wan on gut microbiota in an osteoporotic mouse model
Effects of Zuo-Gui-Wan on osteoporosis. (A) Mouse weight changes over time before and after surgery. The line graph shows the mean ± SD of mouse weight measured weekly for 9 weeks. The surgery was performed at week 1. (n = 7). (B) Serum levels of phosphorus (P), calcium (Ca), alanine transaminase (ALT), aspartate transaminase (AST), creatinine (CREA), and bone alkaline phosphatase (BALP). (n = 7). (C) Representative micro-CT images of the distal femoral trabeculae. The red dashed area represents the region used for three-dimensional reconstruction. (D) Microstructural parameters of ROI in the distal femoral trabeculae for each group. (n = 5). (E) Hematoxylin and eosin (H&E) staining of distal femur sections. (n = 7). (F) Quantitative analysis of the trabecular bone area of the total tissue volume in the region of interest of HE images. (n = 7). (“ns”: no significant difference; ∗: P < 0.05; ∗∗: P < 0.01)