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Fig. 8 | Journal of Orthopaedic Surgery and Research

Fig. 8

From: Ferrostatin-1 inhibits osteoclast differentiation and prevents osteoporosis by suppressing lipid peroxidation

Fig. 8

Fer-1 inhibits lipid peroxidation in OVX mice. (A) Concentration of MDA in serum of each group. (B) Protein expression of ACSL4 and LPCAT3 in bone tissue of each group through Western Blot. (C-D) The band density ratio of ACSL4 and LPCAT3 to β-actin in Western Blot quantified by densitometry. (E-F) Relative mRNA expression of ACSL4 and LPCAT3 in BMMs of each group. (G) Immunofluorescence staining of bone tissue sections of each group. Scale bar = 100 μm. Data are presented as mean ± SD. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001, ns = not statistically significant

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