Table 7 Comparison of sterile commercially available amphotericin powder preparations
From: Evaluation and testing of polymethylmetacrylic (PMMA) bone cements with admixed Amphotericin B
Amphotericin B | Dosage form | Manufacturer/ Product name | Amphotericin B in mg active substance | Total weight |
|---|---|---|---|---|
l-Amphotericin B | Powder for infusion+ | Gilead science GmbH AmBisome® | 50 mg | 1.33 g |
c-Amphotericin B | Powder for infusion | Cephlapharm (before Bristol-Myers Squibb) Amphotericin B | 52 mg | 114 mg |
Amphotericin B colloidal dispersion (c-Amphotericin B) | Powder lyophilized | InterMune, Inc. Amophotec® | 50 mg | 1.03 g |
Amphotericin B lipid-complex | Concentrate for Suspension for Infusion | Cephalon Abelcet® (no longer on the market) | 5 mg/ml a vial containing 20 ml (100 mg Amphotericin B | N/A |
c-Amphotericin B | Powder for sterile concentrate | Neon Healthcare Limited Fungizone® | 50 mg | N/A Inquired with the manufacturer |