| PAI + iPACK(n = 300) | PAI only(n = 300) | p-value |
---|---|---|---|
Opioid related- Adverse events | |||
 Constipation | 4 (1.3%) | 21 (7.0%) | 0.001 |
 Dry mouth | 0 | 0 |  |
 Dizziness | 5 (1.7%) | 21 (7.0%) | 0.001 |
 Skin rash | 0 | 4 (1.3%) | 0.132 |
 Urinary retention | 0 | 3 (1.0%) | 0.247 |
 Respiratory depression | 0 | 0 |  |
 Sedative | 0 | 1 (0.3%) | 1.000 |
Non Opioid related- Adverse events | |||
 Nerve Palsy | 0 | 0 |  |
 Dyspepsia/GI bleeding | 9 (3.0%) | 5 (1.7%) | 0.279 |
 Reoperation | 6 (2.0%) | 5 (1.7%) | 1.000 |