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Fig. 1 | Journal of Orthopaedic Surgery and Research

Fig. 1

From: Transcriptome sequencing–based analysis of the molecular mechanism underlying the effect of lncRNA AC003090.1 on osteoporosis

Fig. 1

Transcriptome sequencing analysis results. (A) FPKM density map. The horizontal coordinate is the log10 (FPKM) value of the gene. The ordinate is the density of the number of genes expressed corresponding to the log10 (FPKM) value. (B) Violin diagram. The horizontal line in the middle of each box is the median value of log10 (FPKM), the upper and lower edges of the box are 75% of the value of log10 (FPKM), and the upper and lower limits are 90% of the value of log10 (FPKM). The width represents the number of genes at this log10 (FPKM) value, that is, the density. (C) Volcano map of expression genes. The horizontal coordinate is log2(FoldChange) and the vertical coordinate is -log10(p-value). The two vertical dashed lines in the figure represent the threshold of 2x expression difference. The dashed line indicates the P-value = 0.05 threshold. Red dots indicate up-regulated genes in the Treat group compared to the Control group, blue dots indicate down-regulated genes in the TREAT group, and gray dots indicate non-significant differentially expressed genes. (D) Heat map of cluster analysis. Each column represents a sample, with genes represented horizontally, high-expressed genes in red and low-expressed genes in green. A represents spongy bone samples from OP patients, aa represents cortical bone samples from OP patients. B represents spongy bone samples of control group, and bb represents cortical bone samples of control group. Each group contains 6 samples, and the numbers represent different samples.

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X