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Fig. 6 | Journal of Orthopaedic Surgery and Research

Fig. 6

From: Transcriptome sequencing–based analysis of the molecular mechanism underlying the effect of lncRNA AC003090.1 on osteoporosis

Fig. 6

LncRNA AC003090.1 affects GSK-3β/β-catenin/c-myc signaling in hBMSCs through the miR-203a-3p/FOXP1 axis (A) RT-qPCR was used to detect Runx2, Opn and Ocn transcription levels of hBMSCs treated with different treatments. (B) RT-qPCR was used to detect the transcription levels of β-catenin, GSK-3β and c-myc in different treated hBMSCs. (C) Western blot detection of β-catenin, GSK-3β and C-myc protein expression levels of hBMSCs treated with different treatments, compared with GAPDH. The data of hBMSCs + lnc-OE group were normalized. ns, no significant difference; *P < 0.05; ** P < 0.01; ***P < 0.001

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X