Table 1 Baseline characteristics of patients grouped by semaglutide exposure
|  | Semaglutide (n = 71) | Control (n = 1947) | P value |
|---|---|---|---|
Age, years | 38.0 ± 7.8 | 36.7 ± 7.6 | 0.154 |
Sex, No. (%) | Â | Â | Â |
 Male | 33 (46.5) | 776 (39.9) | 0.263 |
 Female | 38 (53.5) | 1171 (60.1) |  |
BMI, kg/m2 | 25.6 ± 3.7 | 25.0 ± 4.0 | 0.215 |
Duration since the first ankle sprain, months | 47.7 ± 20.8 | 47.1 ± 19.2 | 0.810 |
Duration since the last ankle sprain, months | 19.5 ± 15.5 | 20.1 ± 14.9 | 0.748 |
Hypertension, No. (%) | Â | Â | Â |
 Yes | 15 (21.1) | 347 (17.8) | 0.476 |
 No | 56 (78.9) | 1600 (82.2) |  |
Smoking | Â | Â | Â |
 Yes | 6 (8.5) | 212 (10.9) | 0.516 |
 No | 65 (91.5) | 1735 (89.1) |  |
Grades of anterior drawer test, No. (%) | Â | Â | Â |
 I (stable) | 38 (53.6) | 1142 (58.7) | 0.587 |
 II (partially unstable) | 28 (39.4) | 653 (33.5) |  |
 III (completely unstable) | 5 (7.0) | 152 (7.8) |  |
Inversion talar tilt test, No. (%) | Â | Â | Â |
 I (stable) | 51 (71.8) | 1497 (76.9) | 0.576 |
 II (partially unstable) | 18 (25.4) | 414 (21.3) |  |
 III (completely unstable) | 2 (2.8) | 36 (1.8) |  |
T2DM, No. (%) | Â | Â | Â |
 Yes | 31 (43.7) | 157 (8.1) | < 0.001 |
 No | 40 (56.3) | 1790 (91.9) |  |
FAAM sports subscale | 63.1 ± 14.2 | 63.0 ± 14.4 | 0.952 |
FAAM ADL subscale | 72.9 ± 11.8 | 71.4 ± 11.4 | 0.282 |
FAOS pain subscale | 83.9 ± 8.9 | 82.3 ± 9.3 | 0.160 |
FAOS symptom subscale | 69.3 ± 14.3 | 70.4 ± 15.5 | 0.577 |
FAOS ADL subscale | 74.7 ± 14.3 | 72.6 ± 12.5 | 0.228 |
FAOS sports subscale | 62.8 ± 14.3 | 63.7 ± 13.6 | 0.610 |
FAOS QoL subscale | 54.2 ± 13.3 | 56.2 ± 15.6 | 0.297 |
CAIT | 15.5 ± 4.3 | 15.8 ± 4.4 | 0.532 |