Fig. 6

HUVEC-exosomal Manf relieved bone loss from osteoporosis. A Representative μCT images of femora from OVX mice treated with PBS or HUVEC exos^Manf, scale bar = 300 nm. B Quantitative μCT analysis of Fig. 6A. C Expression levels of P65 in the femur of OVX mice treated with PBS or HUVEC exos^Manf. D Representative images of TRAP staining in OVX mice femora treated with PBS or HUVEC exos.^Manf, scale bar = 300 nm. E Quantitative analysis of the number of osteoclasts (OCs) on trabecular bone surface in Fig. 6C. n = 7 per group. (*P < 0.05)