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Fig. 4 | Journal of Orthopaedic Surgery and Research

Fig. 4

From: MYLK-AS1 improves fracture by targeting miR-146a-5p to regulate cell viability and apoptosis in osteoblasts

Fig. 4

Targeted binding of MYLK-AS1 to miR-146a-5p. A MYLK-AS1 is mainly enriched in cytoplasmic; B Predicted binding site of MYLK-AS1 to miR-146a-5p; C miR-146a-5p mimic causes reduced luciferase activity in MYLK-AS1-WT; D Both miR-146a-5p and MYLK-AS1 were predominantly enriched in anti-Ago-2; E miR-146a-5p is predominantly enriched in Bio-MYLK-AS1-probe; F miR-146a-5p shows a typical negative correlation with MYLK-AS1 expression; G High expression of MYLK-AS1 leads to reduced miR-146a-5p levels (*** P < 0.001, ****P < 0.0001)

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X