Fig. 4

Differences in molecular and immune infiltration characteristics between the high- and low-risk groups. A Validating the impact of prognostic genes on OS cell proliferation based on the cancer dependency map. B GSEA of KEGG in the high- and low-risk groups. C Heatmap depicting immune cell infiltration in the high- and low-risk groups. D Differences in the levels of 28 types of immune cell infiltration between the high- and low-risk groups. E Correlation of 28 types of immune cells. F Differences in gene expression of major immune checkpoints between the high- and low-risk groups. *: p < 0.05; **: p < 0.01; ***: p < 0.001; ****: p < 0.0001, ns: not significant. OS, osteosarcoma; GSEA, gene set enrichment analysis; KEGG, Kyoto Encyclopedia of Genes and Genomes