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Fig. 4 | Journal of Orthopaedic Surgery and Research

Fig. 4

From: Parthenolide ameliorates glucocorticoid-induced inhibition of osteogenic differentiation and osteoporosis by activating ERK signaling pathway

Fig. 4

PTL accelerates osteogenic differentiation of MC3T3-E1 cells. (A) CCK-8 assay evaluated the viability of MC3T3-E1 cells after treatment with PTL. (B) CCK-8 assay showed the viability of MC3T3-E1 cells after treatment with DEX and PTL. (C-D) ALP staining (7 days) and (E-F) Alizarin Red staining (14 days) in MC3T3-E1 cells treated with DEX and PTL. N = 3. *p < 0.05, **p < 0.01 vs. control or OM group; ##p < 0.01 vs. DEX group. PTL, parthenolide; DEX, dexamethasone; ALP, alkaline phosphatase; OM, osteogenic medium

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X