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Fig. 5 | Journal of Orthopaedic Surgery and Research

Fig. 5

From: Parthenolide ameliorates glucocorticoid-induced inhibition of osteogenic differentiation and osteoporosis by activating ERK signaling pathway

Fig. 5

PTL increases bone mass and the number of osteoblasts in GIOP rat model. (A) H&E staining of the proximal femurs. Calculation of bone morphometric parameters including (B) Tb.Ar, (C) Tb.N, (D) Tb.Sp, and (E) N.ob/BS in the femurs. N = 10. **p < 0.01 vs. control group; #p < 0.05, ##p < 0.01 vs. DEX group. PTL, parthenolide; DEX, dexamethasone; GIOP, glucocorticoid-induced osteoporosis; Tb.Ar, trabecular area ratio; Tb.N, trabecular bone number; Tb.Sp, trabecular separation; N.ob/BS, osteoblast number/bone surface

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X