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Fig. 2 | Journal of Orthopaedic Surgery and Research

Fig. 2

From: TNFRSF11B-modified umbilical cord mesenchymal stem cells as a novel strategy for bone-related diseases by suppressing osteoclast activity

Fig. 2

Expression of TNFRSF11B during adipogenesis and osteogenesis in UCMSCs. (A) Representative images of ALP and ARS staining in UCMSCs following osteogenic induction are shown (Scale bar: 200 μm). (B) qRT-PCR analysis was conducted to assess the expression levels of RUNX2, BSP, OCN, and TNFRSF11B in UCMSCs cultured in osteogenic media for 16 days. (C) Representative images of Oil Red O staining in UCMSCs subjected to adipogenic induction for 25 days are displayed (Scale bar: left, 200 μm; right, 100 μm). (D) The mRNA expression levels of FABP4, PPARγ, and TNFRSF11B were quantified utilizing qRT-PCR. Expression levels were compared to day 0, *p < 0.05; **p < 0.01

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X