Fig. 7

GO and KEGG functional annotation of DEPs. (A–F) GO enrichment analysis of DEPs between the control-CM and TNFRSF11B-OE-CM groups. Chord diagrams and bubble plots illustrate the GO enrichment analysis of DEPs, categorized into BP (A, B), MFs (C, D), and CCs (E, F). (G, H) KEGG pathway enrichment analysis of downregulated DEPs. (I) KEGG pathway analysis of DEPs highlights a notable variation in the TCA cycle between the control-CM and TNFRSF11B-OE-CM groups