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Table 1 Baseline demography characteristics in two cohorts

From: Perioperative blood loss of sequential administration of hemocoagulase Agkistrodon and Tranexamic acid for primary total knee arthroplasty: a randomized controlled trial

Projects

HCA and TXA (n = 29)

TXA only (n = 30)

P value

Age (years) a

65.9 ± 7.8

66.3 ± 6.2

0.812

Gender (male/female) b

23-Jun

24-Jun

> 0.999

BMI a

26.4 ± 2.5

27.0 ± 3.1

0.4

Length of hospitalization (days) a

6.0 ± 0.5

6.1 ± 0.4

0.536

Postoperative hospital stay (days) a

3.1 ± 0.3

3.1 ± 0.4

0.839

Comorbidities b

   

 Hypertension

9

8

0.779

 Diabetes

2

2

> 0.999

 Chronic bronchitis

1

0

> 0.999

 Anemia

0

1

> 0.999

 Autoimmune disease

1

1

> 0.999

 Osteoporosis

11

13

0.793

Preoperative laboratory values a

   

 Hematocrit (%)

41.7 ± 2.8

41.6 ± 3.6

0.98

 Hemoglobin (g/L)

133.5 ± 11.2

133.9 ± 13.5

0.898

 Platelet counts (10^9/L)

204.1 ± 63.2

188.5 ± 54.4

0.313

 Thrombin time (s)

17.2 ± 0.8

17.1 ± 0.7

0.772

 APTT (sec)

25.7 ± 2.3

25.6 ± 2.0

0.835

 INR

0.97 ± 0.05

0.95 ± 0.06

0.284

 PT (sec)

10.7 ± 0.6

10.5 ± 0.7

0.485

 Fibrinogen(g/L)

2.9 ± 0.6

3.0 ± 0.4

0.699

 FDP(mg/L)

2.8 ± 1.3

2.9 ± 1.9

0.742

 D-dimers (mg/L)

0.71 ± 1.12

0.57 ± 0.49

0.889

 Total protein (g/L)

72.4 ± 4.1

72.2 ± 4.6

0.622

 Albumin(g/L)

45.7 ± 3.2

45.6 ± 2.9

0.876

 CRP (mg/L)

4.2 ± 2.1

3.6 ± 2.6

0.133

 IL-6 (pg/ml)

4.2 ± 2.8

3.3 ± 1.6

0.163

Pain VAS score a

5.2 ± 1.8

4.9 ± 1.1

0.305

  1. a The values are given as mean ± standard deviation; b The values are given as numbers;
  2. BMI, body mass index; APTT, activated partial thromboplastin time; INR, international normalized ratio; PT, prothrombin time; FDP, fibrin degradation products; CRP, C-reactive protein; IL-6, interleukin 6; VAS, visual analogue scale;