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Table 1 The demographic and clinical characteristics (N = 2387)

From: Elevated albumin: a protective factor against mortality in geriatric hip fracture patients

Admission Albumin (g/L)

Low group (< 35 g/L)

Medium group (≥ 35 g/L, < 40 g/L)

High group (≥ 40 g/L)

P-value

P-value*

No. of patients

521

1179

687

  

Age (years)

81.63 ± 6.87

79.89 ± 6.51

77.29 ± 6.61

< 0.001

< 0.001

Sex

   

0.068

-

 Male

181 (34.74%)

399 (33.84%)

201 (29.26%)

  

 Female

340 (65.26%)

780 (66.16%)

486 (70.74%)

  

Occupation

   

0.703

-

 Retirement

293 (56.24%)

692 (58.69%)

401 (58.37%)

  

 Farmer

127 (24.38%)

287 (24.34%)

158 (23.00%)

  

 Other

101 (19.39%)

200 (16.96%)

128 (18.63%)

  

History of allergy

   

0.309

-

 No

495 (95.01%)

1138 (96.52%)

657 (95.63%)

  

 Yes

26 (4.99%)

41 (3.48%)

30 (4.37%)

  

Injury mechanism

   

0.729

-

 Falling

501 (96.16%)

1144 (97.03%)

662 (96.36%)

  

 Accident

14 (2.69%)

28 (2.37%)

20 (2.91%)

  

 Other

6 (1.15%)

7 (0.59%)

5 (0.73%)

  

Fracture classification

   

< 0.001

-

 Intertrochanteric fracture

414 (79.46%)

877 (74.39%)

414 (60.26%)

  

 Femoral neck fracture

89 (17.08%)

272 (23.07%)

261 (37.99%)

  

 Subtrochanteric fracture

18 (3.45%)

30 (2.54%)

12 (1.75%)

  

aCCI

   

< 0.001

-

 2

6 (1.15%)

38 (3.22%)

60 (8.73%)

  

 3

65 (12.48%)

225 (19.08%)

174 (25.33%)

  

 4

218 (41.84%)

495 (41.98%)

254 (36.97%)

  

 5

151 (28.98%)

293 (24.85%)

139 (20.23%)

  

 6

65 (12.48%)

98 (8.31%)

44 (6.40%)

  

 7

14 (2.69%)

25 (2.12%)

14 (2.04%)

  

 8

2 (0.38%)

4 (0.34%)

2 (0.29%)

  

 9

0 (0.00%)

1 (0.08%)

0 (0.00%)

  

Hypertension

   

0.052

-

 No

285 (54.70%)

608 (51.57%)

328 (47.74%)

  

 Yes

236 (45.30%)

571 (48.43%)

359 (52.26%)

  

Diabetes Mellitus

   

0.018

-

 No

429 (82.34%)

955 (81.00%)

525 (76.42%)

  

 Yes

92 (17.66%)

224 (19.00%)

162 (23.58%)

  

CHD

   

0.282

-

 No

231 (44.34%)

572 (48.52%)

324 (47.16%)

  

 Yes

290 (55.66%)

607 (51.48%)

363 (52.84%)

  

Arrhythmia

   

0.004

-

 No

318 (61.04%)

813 (68.96%)

468 (68.12%)

  

 Yes

203 (38.96%)

366 (31.04%)

219 (31.88%)

  

Hemorrhagic stroke

   

0.95

-

 No

509 (97.70%)

1154 (97.88%)

673 (97.96%)

  

 Yes

12 (2.30%)

25 (2.12%)

14 (2.04%)

  

Ischemic stroke

   

0.438

-

 No

361 (69.29%)

835 (70.82%)

499 (72.63%)

  

 Yes

160 (30.71%)

344 (29.18%)

188 (27.37%)

  

Cancer

   

0.015

-

 No

496 (95.20%)

1147 (97.29%)

673 (97.96%)

  

 Yes

25 (4.80%)

32 (2.71%)

14 (2.04%)

  

Associated injuries

   

0.007

-

 No

468 (89.83%)

1107 (93.89%)

644 (93.74%)

  

 Yes

53 (10.17%)

72 (6.11%)

43 (6.26%)

  

Dementia

   

< 0.001

-

 No

482 (92.51%)

1136 (96.35%)

671 (97.67%)

  

 Yes

39 (7.49%)

43 (3.65%)

16 (2.33%)

  

COPD

   

< 0.001

-

 No

480 (92.13%)

1088 (92.28%)

667 (97.09%)

  

 Yes

41 (7.87%)

91 (7.72%)

20 (2.91%)

  

Hepatitis

   

0.025

-

 No

495 (95.01%)

1150 (97.54%)

665 (96.80%)

  

 Yes

26 (4.99%)

29 (2.46%)

22 (3.20%)

  

Gastritis

   

0.834

-

 No

512 (98.27%)

1161 (98.47%)

674 (98.11%)

  

 Yes

9 (1.73%)

18 (1.53%)

13 (1.89%)

  

Treatment strategy

   

< 0.001

-

 Conservation

76 (14.59%)

85 (7.21%)

34 (4.95%)

  

 ORIF

354 (67.95%)

832 (70.57%)

401 (58.37%)

  

 HA

89 (17.08%)

254 (21.54%)

228 (33.19%)

  

 THA

2 (0.38%)

8 (0.68%)

24 (3.49%)

  

Albumin (g/L)

32.12 ± 2.36

37.53 ± 1.40

42.31 ± 1.98

< 0.001

< 0.001

Time to admission (hours)

135.35 ± 274.20

77.37 ± 280.78

41.58 ± 181.27

< 0.001

< 0.001

Time to operation (days)

4.67 ± 2.91

4.25 ± 2.53

4.11 ± 2.25

0.001

0.002

Operation time (mins)

98.48 ± 43.34

92.83 ± 36.22

95.02 ± 34.22

0.025

0.053

Blood loss (mL)

257.62 ± 171.59

248.40 ± 158.33

230.66 ± 147.45

0.015

0.254

Infusion (mL)

1558.55 ± 417.30

1552.06 ± 387.20

1598.42 ± 368.85

0.053

0.003

Transfusion (U)

1.56 ± 1.30

1.18 ± 1.26

0.79 ± 1.16

< 0.001

< 0.001

Follow-up (months)

33.75 ± 20.39

38.72 ± 18.51

38.74 ± 16.64

< 0.001

< 0.001

In-hospital mortality

11 (2.11%)

21 (1.78%)

15 (2.18%)

0.805

-

Mortality

   

< 0.001

-

 Survival

261 (50.10%)

804 (68.19%)

535 (77.87%)

  

 Dead

260 (49.90%)

375 (31.81%)

152 (22.13%)

  
  1. Mean + SD/N(%). P-value*: For continuous variables, we used the Kruskal Wallis rank-sum test and Fisher’s exact probability test for count variables with a theoretical number of < 10
  2. aCCI, age-adjusted Charlson Comorbidity Index; CHD, coronary heart disease; COPD, chronic obstructive pulmonary disease; ORIF, open reduction and internal fixation; HA, hemiarthroplasty; THA, total hip arthroplasty