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Table 2 Methodology of in-vitro testing

From: Correction: Evaluation and testing of polymethylmetacrylic (PMMA) bone cements with admixed Amphotericin B

Cement formulation

Test/Limit

Compressive Strength [MPa]

Bending Modulus [MPa]

Bending Strength [MPa]

Impact/Strength [kJ/m2]

Elution in µg per sample

< 70 Mpa

< 1800 Mpa

< 50 Mpa

< 2.5kJ/m2

Palacos R plain

 

Palacos R +

0.5 g pure Amphothericin B

    

Palacos R +

0.8 g pure Amphothericin B

 

Palacos R +

30 mg active ingredient/0,8 g AmBisome®

 

Palacos R + G plain

 

Palacos R + G +

0.8 g pure Amphothericin B

 

Palacos R + G +

30 mg active ingredient/0,8 g AmBisome®

 

Palacos R + G +

2.66 g pure Amphothericin B

 

Palacos R + G +

100 mg active ingredient 2,66 g AmBisome®

 

Copal G + C plain

 

Copal G + C +

50 mg active ingredient/1,33 g AmBisome®