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  1. The spinal endoscopic technique has been extensively documented in decompression procedures for treating lumbar degenerative diseases. However, there is limited literature on the spinal endoscopic in lumbar fu...

    Authors: Lihui Yang, Baodong Wang, Lei Zang, Peng Du, Shuo Yuan, Ning Fan and Qichao Wu
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:286
  2. HMS is characterized by excessive joint mobility, presenting various physical and psychological challenges. Understanding the interplay between these factors is essential for effective HMS management. This stu...

    Authors: Mohammad A. ALMohiza and Ravi Shankar Reddy
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:285
  3. Meniscectomy is a common knee surgery for meniscal tear, and is associated with progressive osteoarthritis (OA). There are few literatures focus on the use of lateral unicompartmental knee arthroplasty (UKA) f...

    Authors: Tao Yang, Huaming Xue, Tong Ma, Tao Wen, Long Xue and Yihui Tu
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:284
  4. This study aims to evaluate the effects of miR-374-5p on osteogenesis in rat osteoblasts, validate its target on PTEN, and explore its role in the PTEN/PI3K/AKT signaling pathway during osteoblast differentiat...

    Authors: Guangning Long, Fen Liu, Hongmeng Cheng, Jun Guo, Pei Wang, Yunfei Luo, Zhihua Li and Fei Tong
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:283
  5. Radial Extracorporeal Shock Wave Therapy (rESWT) is applied as a conservative treatment modality in orthopedics, yet its effectiveness in addressing aseptic loosening of cementless joint prostheses remains unc...

    Authors: Fengnian Zhao, Yufei Chen, Ao Dong and Keguan Song
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:282
  6. Knee osteoarthritis often leads to varus deformity, disrupting lower limb alignment and potentially causing ankle osteoarthritis. While total knee arthroplasty (TKA) can correct knee alignment and improve ankl...

    Authors: Hongxu Li, Haoyang Liu, Yu Zhou, Bailiang Wang and Jinhui Ma
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:281
  7. MicroRNAs have a crucial part to play in maintaining bone formation, signaling, and repair. This research explored the involvement miR-138-5p in modulating osteoblast differentiation in femoral fractures model.

    Authors: Guangming Dai, Wei Jiang, Bo Feng and Lan Zhang
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:280
  8. Mogroside V (MV) is a triterpene glucoside that reportedly exhibits an array of antitumor, anti-inflammatory, hypolipidemic, and hypoglycemic properties. In prior studies, our group determined that MV was able...

    Authors: Dongni Lan, Kongmei Li, Zhimao Ye, Yicai Luo, Cuiping Li and Hao Li
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:278
  9. Kinematic alignment (KA) unicompartmental knee arthroplasty (UKA), which has not been widely adopted in clinical practice, aims to implant a more personalized and physiologically compatible mobile-bearing UKA ...

    Authors: Chong Li, Mengyu Chen, XiangYing Wang, SongHua Yan, Kuan Zhang and Ji Zhou Zeng
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:277
  10. Despite the availability of many highly accurate biomarkers and novel criteria, serum C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) are still the basis for diagnosing periprosthetic joint i...

    Authors: Dariusz Grzelecki, Maciej Kocon, Rafał Mazur, Aleksandra Grajek and Jacek Kowalczewski
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:276
  11. Spinal cord injury (SCI) is a debilitating condition that can result in permanent disability. Neuromodulation is a promising technology that has gained popularity as a treatment for SCI. This study aims to ana...

    Authors: Shutao Gao, Yukun Hu, Shizhe Li, Wei Li and Weibin Sheng
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:275
  12. Kinesiotaping (KT), with its non-restrictive nature, is a preferred treatment option, yet there remains insufficient evidence regarding its effectiveness in managing lateral epicondylitis (LE). This study aims...

    Authors: Halil Ekrem Akkurt, Ramazan Yilmaz, Fatma Sümeyye Suna, Savaş Karpuz and Halim Yilmaz
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:274
  13. Early restoration of muscle strength and knee joint function after anterior cruciate ligament reconstruction (ACLR) is a critical goal in the rehabilitation process. Blood flow restriction training (BFRT), a l...

    Authors: Xiaoyan Li, Fajun Xiao, Hongying Ren, Yi Peng, Fang Feng and Qinjian Dong
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:273
  14. Percutaneous vertebral augmentation is an effective and commonly surgical treatment for osteoporotic vertebral compression fractures, but the problem of bone cement leakage still cannot be prevented. It has be...

    Authors: Chen Jin, Ming-Liang Ning, Rui-Jun Xu, Xiao-Jian Ye, Hao-Jie Chen and Jiang-Ming Yu
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:272
  15. Hip dysplasia (HD) at skeletal maturity can result from residual developmental dysplasia of the hip (DDH) treated in childhood or from primary adolescent-onset HD (AOHD). This study aims to compare the pathomo...

    Authors: Han-Jin Liu, I-Hsin Chen, Ting-Ming Wang, Chia-Che Lee, Sheng-Chieh Lin, Ken N. Kuo and Kuan-Wen Wu
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:271
  16. The treatment of calcaneal fractures is not uniform. This study aimed to compare the functional and imaging results of subtalar joint arthroscopic reduction combined with cannulated screw fixation (SJACF) and ...

    Authors: Hu Yang, Shuo Zhang, Qigang Zhong, Chaoyue Huai, Nan Zhu and Junfeng Zhan
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:270
  17. Cheng He et al. evaluated the effect of dexamethasone combined with vitamin B12 on early outcomes following percutaneous endoscopic interlaminar discectomy (PEID). While the study offers valuable insights, we ...

    Authors: Yinjie Zheng, Fei Gao and Xiaochun Zheng
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:269
  18. Lumbar spinal stenosis (LSS) is a common condition characterized by the narrowing of the spinal canal, often leading to neural compression. Accurate imaging is crucial for diagnosis and surgical planning, with...

    Authors: Raphael Lotan, Michael Shaulov, Itzik Lan, Mojahed Sakhnini, Max Zaidman and Oded Hershkovich
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:268
  19. Distal ulna fractures often occur in conjunction with distal radius fractures and other associated injuries. Currently, there are no satisfactory internal fixation systems available for addressing unstable dis...

    Authors: Chaode Cen, Daqing He, Aixin Cao, Yuehua Xie, Chaoran Hu and Yongfei Cao
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:267
  20. Recently Lisfranc fractures have increased due to increased high-energy injuries from various causes. However, due to incomplete traditional classification, the pattern and distribution of fractures cannot be ...

    Authors: Lei Zhang, Songtao Jiang, Ruihan Wang, Xi Cheng, Wangyu Wu and Guoyou Wang
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:266
  21. Proximal interphalangeal joint (PIPJ) fractures present significant therapeutic challenges in hand surgery. This systematic review evaluated the comparative efficacy of dynamic external fixation against tradit...

    Authors: Chengjing Wang and Changqing Li
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:265
  22. The aim of this study was to compare the efficacy, clinical outcomes, and complications of cable-asisted bone transport (CASt) and circular external fixator-assisted bone transport (CEFt) methods in the manage...

    Authors: Güngör Alibakan, Muharrem Kanar, Raffi Armağan, Yusuf Sülek, Yusuf Altuntaş and Osman Tuğrul Eren
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:264
  23. Retrograde superior ramus screw of pubis (SRSP) is a new kind of pelvic minimally invasive internal fixation apparatus developed by our team. The purpose of this study was to analyze the biomechanical stabilit...

    Authors: Gu Meiqi, Xu Zhe, Li Yifei, Xiang Penghui, Wang Zhen, Zhang Rui, Xin Fei, Tang Zhaohui and Yi Chengla
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:263
  24. Alongside the numerous advantages of arthroplasty surgery, the extensive complications associated with bone cement contact remain serious chemical hazards in the operating room. The present study aims to inves...

    Authors: Leila Sadati, Rana Abjar, Salman Azarsina, Samaneh Doroudian and Fatemeh Tavakoli
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:262
  25. The prevalence of osteoarthritis and postoperative neuropathic pain after arthroplasty highlights the necessity for improved pain management. Many patients develop chronic neuropathic pain, necessitating targe...

    Authors: Miguel Ángel Ruiz Ibán, Ángel Oteo-Álvaro, Xoán Miguéns Vázquez, José Luís Ávila, Hermann Ribera and María Pérez-Páramo
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:261
  26. This study seeks to confirm the therapeutic effectiveness of TRFD in inhibiting adipogenesis and promoting osteogenesis in primary osteoporosis through the MAPK/HIF-1α signaling pathway. C57BL/6J mice underwen...

    Authors: Hui Su, Luyao Liu, Zechen Yan, WenXuan Guo, Guangxin Huang, Rujie Zhuang and Yu Pan
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:260
  27. L5/S1 segment is one of the most common lumbar degenerative segments with high clinical failure rate. When the clinically responsible segment consists of one or more segments including L4/L5 segment, whether t...

    Authors: Yan Liu, Hua-Peng Guan, Juan Yu and Nian-Hu Li
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:259
  28. The sedimentation sign offers an efficient method for evaluating lumbar spinal stenosis. However, limited research exists regarding its applicability to post-operative MRI scans. This study aims to assess the ...

    Authors: Jia Chen, Zhikun Xu, Hao Wu, Zhenhua Feng and Fengdong Zhao
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:258
  29. Vertebral Hounsfield unit (HU) were regarded as a new way to predict fragility fracture. However, HU values were measured in a single plane, which is not accurate for the entire vertebral body. This study aime...

    Authors: Rongkun Chang, Feng Chang, Yang You, Zhaowei Wang, Zhen Geng, Rongcan Liu, Ruopeng Mai, Yinbin Wang and Lijun Cai
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:257
  30. This study aims to compare the outcomes of two-level anterior cervical discectomy and fusion (ACDF) procedures using stand-alone cages versus cage and plate fixation in patients diagnosed with cervical disc he...

    Authors: Cem Sever, Bekir Eray Kilinc, Ahmet Onur Akpolat, Tayfun Bozkaya, Akif Kurtan and Abdulhamit Misir
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:256
  31. Destabilizing injuries to the deltoid ligament have relied on radiographic stress examination for diagnosis, with a focus on medial clear space widening. Increasingly, Portable ultrasound has also been used in...

    Authors: Jirawat Saengsin, Pongpanot Sornsakrin, Pichitchai Atthakomol, Go Sato, Bart Lubberts, Gregory Waryasz, Christopher W. DiGiovanni and Daniel Guss
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:254
  32. Osteosarcoma (OS) is the most common primary bone malignancy because of its extra high tendency of metastasis. In-depth research is needed to uncover the pathogenesis of patients with OS cells. We collected 74...

    Authors: Menglin Cong, Shufeng Li, Yu Fu, Ting Wang, Huizhen Wei, Xiaojie Ma, Fangming Liu, XieHuang Sheng, Kehan Long, Haocheng Hou, Xuecheng Sun, Weiwei Li and Lei Zhang
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:253
  33. Surgical site infections (SSIs) after limb amputations have been associated with increased patient morbidity, mortality and costs. This study aimed to determine the incidence, bacteriological profile and predi...

    Authors: Haitham Hamudu, Helmut Nyawale, Vitus Silago, Mariam M. Mirambo, Phillipo L. Chalya and Stephen E. Mshana
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:252
  34. Current clinical studies on femoral head necrotic lesions primarily focus on the medial and lateral regions, while detailed MRI-based methods to evaluate the relationship between anterior or posterior necrosis...

    Authors: Yawei Dong, Yan Yan, Jun Zhou, Kaiqiang Tang, Xiaohan Wang, Rui Quan, Jiaming Lin, Yan Jia, Zelu Zheng, Baohong Mi and Weiheng Chen
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:251
  35. Patients with osteoporotic fractures will further lose bone mineral density and the incidence of refractures will be greatly increased, which is one of the leading causes of death and disability in the elderly...

    Authors: Mingzhe Yu, Pei Zhou, Yanjun Che and Yuan Luo
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:250
  36. The emergence of multidrug-resistant bacteria has resulted in more complicated disease courses and worsening prognoses for patients with acute hematogenous osteomyelitis (AHO), increasing the necessity for sur...

    Authors: Jiale Guo, Wei Feng, Baojian Song, Danjiang Zhu, Yuwei Wen and Qiang Wang
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:249
  37. Anterior cruciate ligament (ACL) injuries are exceedingly common among soccer players and severely impact their careers and health. This study evaluates the effects of injury risk reduction programs, including...

    Authors: Wenbo Su, Jing Wang, Yuxuan Ying, Bin Lu, Hangbing Liu, Zixiang Zhou, Chang Liu and Hezhang Yun
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:248
  38. With a growing number of elderly patients requiring elective and non-elective procedures, frailty-based preoperative risk stratification is an emerging tool in orthopedic surgery to minimize adverse postoperat...

    Authors: Nithin K. Gupta, Forrest Dunivin, Hikmat R. Chmait, Chase Smitterberg, Azhaan Buttar, Moiz Fazal-ur-Rehman, Taylor Manes, Morgan Turnow, Tyler K. Williamson, Benjamin C. Taylor, Jack W. Weick and Christian Bowers
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:247
  39. Antibiotic-loaded bone cement (ALBC) is crucial for treating orthopedic infections, but its use is limited by suboptimal antibiotic release patterns and potential toxicity. This study explores the dual additio...

    Authors: Tzu-Hao Tseng, Chih-Hao Chang, Chien-Lin Chen, Hongsen Chiang, Jyh-Horng Wang and Tai-Horng Young
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:246
  40. Bone cement is a research hotspot and has been partially applied in the field of bone repair thanks to the good mechanical, physical and antibacterial properties. However, the easy wear and high temperature du...

    Authors: Hong Wang, Kangrui Zhang, Wenduo Niu, Sicong Min, Fan Lu, Shifeng Zhang, Wensheng Gao, Hua Han and Yayi Xia
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:245
  41. Anterior cruciate ligament deficiency (ACLD) has traditionally been regarded as a contraindication for unicompartmental knee arthroplasty (UKA). However, advancements in surgical techniques and improvements in...

    Authors: Shuhan Jia, Di Long, Bo Zhang, Mingyang Sun, Fengji Liu, Yixuan Jiao, Guoan Wang and Bin Zhang
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:244
  42. Whether patients with chronic ankle instability (CAI) can benefit from weight loss yielded by using glucagon-like peptide-1 receptor agonists (GLP1-RAs) has remained unclear.

    Authors: Jieyuan Zhang, Cheng Wang, Jiazheng Wang, Wenqi Gu, Haiqing Wang, Hongyi Zhu, Xin Ma and Zhongmin Shi
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:243
  43. BMSCs with robust osteogenic differentiation capacity can participate in the repair of osteoporotic (OP) bone. Long non-coding RNAs (LncRNAs) serve as crucial regulators of osteogenic differentiation. This stu...

    Authors: Shanglong Ning, Yang Chen and Hui Zhu
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:242
  44. The study assessed the efficacy of percutaneous pedicle screw fixation (PPSF) as a treatment approach for monosegmental pyogenic spondylodiscitis (PS), particularly in patients with compromised health conditio...

    Authors: Zhen-Zhong Chen, Ke-Jun Zhu, Bin Pan, Chao Lou, Wei-Yang Yu and Deng-Wei He
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:241
  45. This study explored the anatomical variations and clinical implications of accessory ossicles in the spine, which are often identified incidentally but can significantly impact the differential diagnosis of sp...

    Authors: Eren Ogut
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:240
  46. There is a wide discrepancy in the literature regarding the incidence of postoperative dysphonia following ACDF. How postoperative dysphonia is measured is also inconsistent, with many studies relying on patie...

    Authors: Geena Jung, Jorden Xavier, Shaun Wu, Rachel Schwartz, Rachel Kominsky and Mitchell S. Fourman
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:239
  47. Percutaneous endoscopic unilateral laminotomy and bilateral decompression (Endo-ULBD) has been applied to patients with lumbar spinal canal stenosis (LSS). However, it remains unclear whether gait and postural...

    Authors: Penghui Ke, Liuhu Han, Wenfeng Xu, Yang Song, Benfan Zhu and Likui Wang
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:238
  48. This study was aimed at comparing the efficacy and safety of bicompartmental knee arthroplasty (BKA) and total knee arthroplasty (TKA) in treating bicompartmental knee osteoarthritis through a systematic evalu...

    Authors: Rongwei Zhang, Xianyue Shen, Kangyong Yan, Xianzuo Zhang and Chen Zhu
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:237

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