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Bone morphogenetic protein 9 (BMP9) and nerve growth factor (NGF) are critical factors influencing osteogenic differentiation in mesenchymal stem cells (MSCs). While BMP9 has been recognized for its potent ost...
The spinal endoscopic technique has been extensively documented in decompression procedures for treating lumbar degenerative diseases. However, there is limited literature on the spinal endoscopic in lumbar fu...
HMS is characterized by excessive joint mobility, presenting various physical and psychological challenges. Understanding the interplay between these factors is essential for effective HMS management. This stu...
Meniscectomy is a common knee surgery for meniscal tear, and is associated with progressive osteoarthritis (OA). There are few literatures focus on the use of lateral unicompartmental knee arthroplasty (UKA) f...
This study aims to evaluate the effects of miR-374-5p on osteogenesis in rat osteoblasts, validate its target on PTEN, and explore its role in the PTEN/PI3K/AKT signaling pathway during osteoblast differentiat...
Radial Extracorporeal Shock Wave Therapy (rESWT) is applied as a conservative treatment modality in orthopedics, yet its effectiveness in addressing aseptic loosening of cementless joint prostheses remains unc...
Knee osteoarthritis often leads to varus deformity, disrupting lower limb alignment and potentially causing ankle osteoarthritis. While total knee arthroplasty (TKA) can correct knee alignment and improve ankl...
MicroRNAs have a crucial part to play in maintaining bone formation, signaling, and repair. This research explored the involvement miR-138-5p in modulating osteoblast differentiation in femoral fractures model.
Osteoarthritis (OA) is a common chronic degenerative joint disease. Recent studies have emphasized the crucial role of macrophages, particularly tissue-resident macrophages (Tissue-Resident Macrophages, TRMs),...
Mogroside V (MV) is a triterpene glucoside that reportedly exhibits an array of antitumor, anti-inflammatory, hypolipidemic, and hypoglycemic properties. In prior studies, our group determined that MV was able...
Kinematic alignment (KA) unicompartmental knee arthroplasty (UKA), which has not been widely adopted in clinical practice, aims to implant a more personalized and physiologically compatible mobile-bearing UKA ...
Despite the availability of many highly accurate biomarkers and novel criteria, serum C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) are still the basis for diagnosing periprosthetic joint i...
Spinal cord injury (SCI) is a debilitating condition that can result in permanent disability. Neuromodulation is a promising technology that has gained popularity as a treatment for SCI. This study aims to ana...
Kinesiotaping (KT), with its non-restrictive nature, is a preferred treatment option, yet there remains insufficient evidence regarding its effectiveness in managing lateral epicondylitis (LE). This study aims...
Early restoration of muscle strength and knee joint function after anterior cruciate ligament reconstruction (ACLR) is a critical goal in the rehabilitation process. Blood flow restriction training (BFRT), a l...
Percutaneous vertebral augmentation is an effective and commonly surgical treatment for osteoporotic vertebral compression fractures, but the problem of bone cement leakage still cannot be prevented. It has be...
Hip dysplasia (HD) at skeletal maturity can result from residual developmental dysplasia of the hip (DDH) treated in childhood or from primary adolescent-onset HD (AOHD). This study aims to compare the pathomo...
The treatment of calcaneal fractures is not uniform. This study aimed to compare the functional and imaging results of subtalar joint arthroscopic reduction combined with cannulated screw fixation (SJACF) and ...
Cheng He et al. evaluated the effect of dexamethasone combined with vitamin B12 on early outcomes following percutaneous endoscopic interlaminar discectomy (PEID). While the study offers valuable insights, we ...
Lumbar spinal stenosis (LSS) is a common condition characterized by the narrowing of the spinal canal, often leading to neural compression. Accurate imaging is crucial for diagnosis and surgical planning, with...
Distal ulna fractures often occur in conjunction with distal radius fractures and other associated injuries. Currently, there are no satisfactory internal fixation systems available for addressing unstable dis...
Recently Lisfranc fractures have increased due to increased high-energy injuries from various causes. However, due to incomplete traditional classification, the pattern and distribution of fractures cannot be ...
Proximal interphalangeal joint (PIPJ) fractures present significant therapeutic challenges in hand surgery. This systematic review evaluated the comparative efficacy of dynamic external fixation against tradit...
The aim of this study was to compare the efficacy, clinical outcomes, and complications of cable-asisted bone transport (CASt) and circular external fixator-assisted bone transport (CEFt) methods in the manage...
Retrograde superior ramus screw of pubis (SRSP) is a new kind of pelvic minimally invasive internal fixation apparatus developed by our team. The purpose of this study was to analyze the biomechanical stabilit...
Alongside the numerous advantages of arthroplasty surgery, the extensive complications associated with bone cement contact remain serious chemical hazards in the operating room. The present study aims to inves...
The prevalence of osteoarthritis and postoperative neuropathic pain after arthroplasty highlights the necessity for improved pain management. Many patients develop chronic neuropathic pain, necessitating targe...
This study seeks to confirm the therapeutic effectiveness of TRFD in inhibiting adipogenesis and promoting osteogenesis in primary osteoporosis through the MAPK/HIF-1α signaling pathway. C57BL/6J mice underwen...
L5/S1 segment is one of the most common lumbar degenerative segments with high clinical failure rate. When the clinically responsible segment consists of one or more segments including L4/L5 segment, whether t...
The sedimentation sign offers an efficient method for evaluating lumbar spinal stenosis. However, limited research exists regarding its applicability to post-operative MRI scans. This study aims to assess the ...
Vertebral Hounsfield unit (HU) were regarded as a new way to predict fragility fracture. However, HU values were measured in a single plane, which is not accurate for the entire vertebral body. This study aime...
This study aims to compare the outcomes of two-level anterior cervical discectomy and fusion (ACDF) procedures using stand-alone cages versus cage and plate fixation in patients diagnosed with cervical disc he...
Meniscus injury is one of the most common knee diseases, which is managed through conservative and surgical treatments. In recent years, biotherapy has shown great potential to treat various symptoms caused by...
Destabilizing injuries to the deltoid ligament have relied on radiographic stress examination for diagnosis, with a focus on medial clear space widening. Increasingly, Portable ultrasound has also been used in...
Osteosarcoma (OS) is the most common primary bone malignancy because of its extra high tendency of metastasis. In-depth research is needed to uncover the pathogenesis of patients with OS cells. We collected 74...
Surgical site infections (SSIs) after limb amputations have been associated with increased patient morbidity, mortality and costs. This study aimed to determine the incidence, bacteriological profile and predi...
Current clinical studies on femoral head necrotic lesions primarily focus on the medial and lateral regions, while detailed MRI-based methods to evaluate the relationship between anterior or posterior necrosis...
Patients with osteoporotic fractures will further lose bone mineral density and the incidence of refractures will be greatly increased, which is one of the leading causes of death and disability in the elderly...
The emergence of multidrug-resistant bacteria has resulted in more complicated disease courses and worsening prognoses for patients with acute hematogenous osteomyelitis (AHO), increasing the necessity for sur...
Anterior cruciate ligament (ACL) injuries are exceedingly common among soccer players and severely impact their careers and health. This study evaluates the effects of injury risk reduction programs, including...
With a growing number of elderly patients requiring elective and non-elective procedures, frailty-based preoperative risk stratification is an emerging tool in orthopedic surgery to minimize adverse postoperat...
Antibiotic-loaded bone cement (ALBC) is crucial for treating orthopedic infections, but its use is limited by suboptimal antibiotic release patterns and potential toxicity. This study explores the dual additio...
Bone cement is a research hotspot and has been partially applied in the field of bone repair thanks to the good mechanical, physical and antibacterial properties. However, the easy wear and high temperature du...
Anterior cruciate ligament deficiency (ACLD) has traditionally been regarded as a contraindication for unicompartmental knee arthroplasty (UKA). However, advancements in surgical techniques and improvements in...
Whether patients with chronic ankle instability (CAI) can benefit from weight loss yielded by using glucagon-like peptide-1 receptor agonists (GLP1-RAs) has remained unclear.
BMSCs with robust osteogenic differentiation capacity can participate in the repair of osteoporotic (OP) bone. Long non-coding RNAs (LncRNAs) serve as crucial regulators of osteogenic differentiation. This stu...
The study assessed the efficacy of percutaneous pedicle screw fixation (PPSF) as a treatment approach for monosegmental pyogenic spondylodiscitis (PS), particularly in patients with compromised health conditio...
This study explored the anatomical variations and clinical implications of accessory ossicles in the spine, which are often identified incidentally but can significantly impact the differential diagnosis of sp...
There is a wide discrepancy in the literature regarding the incidence of postoperative dysphonia following ACDF. How postoperative dysphonia is measured is also inconsistent, with many studies relying on patie...
Percutaneous endoscopic unilateral laminotomy and bilateral decompression (Endo-ULBD) has been applied to patients with lumbar spinal canal stenosis (LSS). However, it remains unclear whether gait and postural...
Citation Impact 2023
Journal Impact Factor: 2.8
5-year Journal Impact Factor: 3.0
Source Normalized Impact per Paper (SNIP): 1.182
SCImago Journal Rank (SJR): 0.799
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Journal of Orthopaedic Surgery and Research