Page 4 of 124
The damage to chondrocytes and inflammatory responses are considered the key factors in the pathogenesis of osteoarthritis (OA). Ubiquitin-specific protease 15 (USP15) has been shown to be involved in OA. This...
Unilateral biportal endoscopy (UBE) is gaining popularity owing to its versatility as a spinal endoscopic procedure. However, the general value of the learning curve for discectomy by UBE is unknown. This retr...
To analyze the value of intraoperative neurophysiological monitoring (IONM) in unilateral biportal endoscopic (UBE) lumbar spine surgery.
The aim of this study was to evaluate the clinical outcomes of three surgical methods, three types of arthroscopic suture fixation, suspension fixation with EndoButton, and open screw fixation, in the treatmen...
Knee osteoarthritis is a common degenerative disease in the elderly, and total knee arthroplasty is an effective treatment for end-stage knee joint diseases. However, kinesiophobia after surgery can impede pat...
Halofuginone is an antiprotozoal drug with antifibrotic and anti-inflammatory properties. The aim of our study was to determine the effects of halofuginone on nerve recovery in sciatic nerve injury and compare...
Surgical treatment of suppurative spondylitis requires focus debridement, spinal stability, and deformity correction. Different approaches face challenges like complex anatomical structures and greater trauma....
MicroRNA (miRNA) participates in the pathophysiological processes of multiple metabolic diseases, including gout. In gout patients, there is concomitant derangement of bone metabolism. The study aimed to explo...
Diabetes mellitus (DM) significantly impairs fracture healing, necessitating reliable animal models to study diabetic fracture repair mechanisms and therapeutic interventions. This study aimed to develop and c...
Anxiety impacts patients and healthcare providers during orthopedic procedures, yet virtual reality (VR) and augmented reality (AR) effectiveness remains inconsistently reported, lacking systematic synthesis i...
The Correction to this article has been published in Journal of Orthopaedic Surgery and Research 2025 20:435
The purpose of this study was to compare three-dimensional (3D) and two-dimensional (2D) evaluation of the stress X-rays following total knee arthroplasty (TKA).
The original article was published in Journal of Orthopaedic Surgery and Research 2025 20:151
Chondrocyte apoptosis is associated with the severity of cartilage destruction and matrix degeneration in the progression of osteoarthritis. Increasing evidence indicates that autophagy has a significant cytop...
This study aims to analyze the cumulative incidence and associated risk factors of phobic movement disorder (PMD) after hip fracture internal fixation surgery, with the goal of optimizing postoperative rehabil...
Delayed fracture healing (DFH) is a common postoperative complication in fracture patients, and a validated serum marker may aid in the clinical management and improve the prognosis of fracture patients. In th...
This study aimed to evaluate the differences between the mechanical axis (MA) in standing and supine positions in patients who underwent high tibial osteotomy (HTO) or distal tuberosity osteotomy (DTO) based o...
With an aging population, the prevalence of lumbar spinal diseases necessitating surgical intervention is increasing. Handgrip strength (HGS) has emerged as a simple measure of muscle function that may correla...
Design a new type of external fixation device that is small in size, high in strength, and capable of achieving the mechanical requirements for fracture healing. Verify the rationality and effectiveness of the...
Accurate acetabular cup positioning is essential for successful total hip arthroplasty (THA) outcomes. The conventional mechanical alignment guide (MAG) method provides moderate accuracy. We developed a novel ...
The loss of medial and lateral wall support were the main risk factors of implant failure for proximal femoral fractures. A novel intramedullary nail, called proximal femoral universal nail system (PFUN), was ...
The potential of ultrasound-guided labelling of the inferior patellar branch of the saphenous nerve (IPBSN) to reduce IPBSN injury during anterior cruciate ligament reconstruction (ACLR) has not been explored....
This study investigates the gait characteristics and clinical outcomes following Unicompartmental Knee Arthroplasty (UKA) to provide scientific evidence for optimizing postoperative rehabilitation and patient ...
To explore the application of a new three-dimensional computed tomography measurement (maximum-inscribed-sphere method) in female DDH (developmental dysplasia of the hip) patients with gynecoid and anthropoid ...
The role of N6-methyladenosine (m6A)-modified circRNAs in disease progression is of great significance. However, the specific impact of m6A modification of circSTAT6 on osteoporosis (OP) is still uncertain.
The purpose of this study was to determine if the use of specially designed screw hole inserts in empty locking screw holes improves the strength and failure characteristics of locking plates.
The aim of the current study is to investigate the efficacy and risk factors associated with arthroscopic adhesiolysis in treating elderly traumatic frozen shoulder.
Intervertebral disc degeneration (IVDD) is characterized by a decrease in extracellular matrix (ECM) and water loss, which is a major cause of low back pain (LBP). Electroacupuncture (EA) has long been used to...
Lumbar disc herniation (LDH) is the serious stage of intervertebral disc degeneration (IDD), and the location and degree of intervertebral disc herniation are closely related to clinical symptoms and signs. Ho...
Nonunion of fractures is a major unsolved problem in clinical treatment and prognosis of orthopedics. Bone marrow mesenchymal stem cell (BMSC) exosomes have been proven to be involved in mediating tissue and b...
Retrospective Cohort Study.
Although epidural corticosteroid injections (ESIs) provide short-term relief for lumbar radicular pain caused by disc herniation, concerns remain regarding their long-term efficacy and complications. Platelet-...
Intraoperative neuromonitoring (IONM) alerts are critical concerns for surgeons performing spinal deformity corrective surgeries, as they indicate a heighteded risk of postoperative neurological deficits. Prev...
Allogenous dermal scaffold augmentation enhances partial rotator cuff repairs by providing structural support and a biologic scaffold that promotes tissue regeneration, reduces mechanical strain, and compensat...
Fatty infiltration (FI) in rotator cuff (RC) is detected in many patients with complete RC tears. But there remains controversy on the prognostic effects of FI in RC tears, especially for patients with moderat...
Delayed fracture healing (DFH) affects patients’ quality of life, and there are limitations in diagnosis by CT scan. The purpose of the study is to evaluate the potential and mechanism of clinical application ...
According to the Song classification, the treatment of Song 2 lateral humeral condyle fracture (LHCF) is controversial because the stability of the fracture is difficult to determine. The aim of this study is ...
Osteoarthritis (OA) is the most prevalent arthritic disease characterized by cartilage degradation and low-grade inflammation, for which there remains a lack of efficacious therapeutic interventions. Notably, ...
Total hip arthroplasty (THA) is increasing in low- and middle-income countries (LMICs) due to rising rates of hip fractures and an aging population. Identifying frail patients at risk for postoperative complic...
The Correction to this article has been published in Journal of Orthopaedic Surgery and Research 2025 20:413
Nicotine product use, including cigarette smoking and other nicotine products, is a known risk factor for various health complications. While previous studies have examined its impact on spinal procedures, its...
Full-endoscopic spine surgery (FESS) is generally considered to have a steep learning curve due to its technical complexity. This study aimed to evaluate the learning curve for full-endoscopic decompressive la...
This retrospective study aimed to evaluate the clinical and radiological outcomes of magnesium (Mg) bioabsorbable compression screws in the management of scaphoid fractures and nonunion. Despite theoretical be...
Delayed fracture healing (DFH) is a significant burden for patients. Therefore, early diagnosis and detection are important for the treatment of DFH. The long non-coding RNA (LncRNA) MYLK-AS1 is abnormally exp...
The long-term stability of cementless femoral prostheses is primarily affected by aseptic loosening, micromotion, and stress shielding, all of which are related to the force transfer of the prosthesis. These f...
Although periprosthetic joint infection (PJI) can affect multiple joints simultaneously, most individuals with multiple joint involvement exhibit PJI in only one joint. Data regarding the metachronous PJI mana...
The objective of this study was to identify potential genes implicated in the “peri-collapse” synovium of osteonecrosis of the femoral head through coding gene sequencing and to further clarify their specific ...
Patients who undergo reconstruction for multiligament knee injuries (MLKIs) often exhibit knee instability and poor overall knee function during postoperative follow-up. This may be related to the changes in p...
Differentiation of bone marrow mesenchymal stem cells (BMSCs) is pivotal in the pathogenesis of steroid-induced femoral head osteonecrosis. Icariin, an active ingredient in Epimedii herba, has the potential to...
This systematic review attempts to address survivorship of patellofemoral joint replacements, with conversion to a total knee arthroplasty (TKA) as an endpoint.
This study aimed to explore the correlation between the proton density fat fraction (PDFF) of the infrapatellar fat pad and the severity of knee osteoarthritis (KOA), with a focus on identifying potential imag...
Bone morphogenetic protein 9 (BMP9) and nerve growth factor (NGF) are critical factors influencing osteogenic differentiation in mesenchymal stem cells (MSCs). While BMP9 has been recognized for its potent ost...
Citation Impact 2023
Journal Impact Factor: 2.8
5-year Journal Impact Factor: 3.0
Source Normalized Impact per Paper (SNIP): 1.182
SCImago Journal Rank (SJR): 0.799
Speed 2024
Submission to first editorial decision (median days): 6
Submission to acceptance (median days): 66
Usage 2024
Downloads: 3,946,685
Altmetric mentions: 960
Journal of Orthopaedic Surgery and Research