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  1. Spinal tuberculosis is the most common extrapulmonary tuberculosis, characterized by intervertebral disc destruction, which seriously affects people’s quality of life. Recent studies have suggested that the TG...

    Authors: Feng Li, Hongdong Tan, Xiao Zhang, Xiaodong Zhao, Xiaopeng Li and Gaoyang Chen
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:484
  2. Appropriate treatment of chondral lesions in the hip greatly improves symptoms and reduces the need for early joint replacement in these patients. Whilst the outcomes of Autologous Chondrocyte Transplantation ...

    Authors: Thomas Walker, Maximilian Dewhurst and Peter Bates
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:483
  3. Although an established correlation exists between tumor cell proliferation and elevated polyamine levels, research on polyamine metabolism in osteosarcoma (OS) remains limited. This study aimed to identify po...

    Authors: Shuo Qiu, Chen Tan, Dongdong Cheng and Qingcheng Yang
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:482
  4. The use of multiple layers of vibril under tourniquet cuffs is common. However, these layers can lead to complications. We designed a special waterproof curtain for use under tourniquet cuffs. Its effects on b...

    Authors: Soheila Bakhtiari, Mehdi Teimouri, Nafise Rahimi, Mohammad Hassan Bagheri and Sayyed Yazdan Asadi
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:481
  5. Vertebral fractures are linked to significant disability and mortality risks. Yet, existing studies on their global burden are outdated and lack predictive foresight.

    Authors: Honghui Lei, Zebin Huang, Fangyong Wang, Tao Liu, Yang Yu, Sitong Su, Meiling Cheng and Haoyuan Chen
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:480
  6. Developmental hip dysplasia is a common cause of hip arthrosis in young adults, necessitating total hip arthroplasty (THA) for improved function and pain relief. In cases of high-riding hips, transverse femora...

    Authors: Kutalmis Albayrak, Yakup Alpay, Ozgur Ismail Turk, Muhammed Mert, Deniz Akbulut and Akif Albayrak
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:479
  7. Mesenchymal stem cells (MSCs), possessing multilineage potential, are capable of differentiating into osteoblasts and thus serve as suitable seed cells for bone regeneration. Tumor necrosis factor receptor sup...

    Authors: Mina Ding, Qian Ding, Zhijie Liu, Liang Wang, Ke Pei, Junyuan Hu, Yan Liao and Jian V. Zhang
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:478
  8. Ferroptosis is implicated in various musculoskeletal conditions, including non-traumatic osteonecrosis of the femoral head (NT-ONFH).

    Authors: Qing-He Ye, Peng Zhang, Yong-Heng Zhao, Wen-Xiu Zhu, Hong-Xun Zhu and Biao-Fang Wei
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:477
  9. Temporary epiphysiodesis (tED) around the knee is a well-established treatment approach for leg length discrepancies (LLD) in skeletally immature patients. Moreover, it may be conducted bilaterally to reduce h...

    Authors: Andrea Laufer, Jan Disselkamp, Georg Gosheger, Gregor Toporowski, Adrien Frommer, Veronika Weyer-Elberich, Robert Roedl and Bjoern Vogt
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:476
  10. This study establishes a quantitative anatomical-mechanical-clinical decision-making mapping relationship using the Digital Intelligence Orthopaedic Technology, systematically analyses the dynamic biomechanica...

    Authors: Zhengfeng Jia, Cheng Xu, Weilu Gao, Changsen Yang, Peifu Tang and Jiantao Li
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:475
  11. Thrombus formation is a severe complication in orthopedic surgery, significantly increasing mortality in patients with fractures. Therefore, identifying feature genes to determine thrombus presence in fracture...

    Authors: Guanghua Shi, Xiaocui Shi, Meng Zhang, Rui Cheng, Mengqing Hu, Yu Zhao, Shimei Li, Xiuxiu Li, Haiyun Ma and Pengcui Li
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:474
  12. Carpal Tunnel Syndrome (CTS) is the most common entrapment neuropathy, frequently presenting with pain, numbness, and muscle weakness due to median nerve compression. However, diagnosing CTS becomes particular...

    Authors: Hamed Naghizadeh, Omid Salkhori, Shahram Akrami, Seyyed saeed Khabiri and Aidin Arabzadeh
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:473
  13. This systematic review aims to further explore the relationship between image and clinical features of spinal gas accumulation, propose a novel clinical classification based on CT images and clinical outcomes ...

    Authors: Xin Chen, Jingming Wang, Lei Wang, Xiaoduo Xu, Qinglei Gong and Weimin Huang
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:472
  14. Dystrophic neurofibromatosis type I (NF1) kyphoscoliosis presents unique challenges for corrective spinal surgery due to anatomical abnormalities. To compare the radiographic and clinical outcomes of dystrophi...

    Authors: Yuan-Shun Lo, Yu-Tong Dai, Yong Qiu, Erh-Ti Ernest Lin, Hung-Lun Hsieh, Xue-Peng Wei, Chun-Hao Tsai, Yi-Chin Fong, Hsien-Te Chen, Shiau-Tzu Tzeng and Ben-Long Shi
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:470
  15. Osteoporosis is a systemic metabolic degenerative bone disease characterised by decreased bone mass, impaired bone microstructure, weakened bone strength and susceptibility to fracture. In China, the preventio...

    Authors: Bo Liu, Xue Mao, Zhe-Jian-Yi Gao and Huan Wang
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:469
  16. The aim of this study was to compare the performance of artificial intelligence (AI) in detecting distal radius fractures (DRFs) on plain radiographs with the performance of human raters.

    Authors: Nikolai Ramadanov, Patric John, Robert Hable, Andreas Georg Schreyer, Simon Shabo, Robert Prill and Mikhail Salzmann
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:468
  17. Osteoarthritis (OA) is a common degenerative joint disease causing chronic pain, disability, and mobility limitations, severely affecting quality of life. Traditional treatments like physical therapy and surge...

    Authors: Tao Wang, Mingyang Jiang, Sichang Wu, Ke Zhang, Raul Romero Del Rey, Ruqiong Wei and Raquel Alarcón Rodríguez
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:467
  18. Total Hip Arthroplasty (THA) is the gold standard for treating end-stage hip osteoarthritis. Robotic-assisted systems, particularly the MAKO system, have been introduced to enhance reproducibility and safety. ...

    Authors: Ryan Wai Keong Loke, Yao Hui Lim, Yang Kai Chan and Barry Wei Loong Tan
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:466
  19. The treatment of acetabular fractures ranges from non-operative with no restrictions in mobilisation to some of the more complex operative treatments in orthopaedics. Treatment strategies are developing, and o...

    Authors: Madelene Albrektsson, Michael Möller, Mikael Sundfeldt, David Wennergren and Olof Wolf
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:465
  20. The use of rigid braces and specialized exercises for the treatment of adolescent idiopathic scoliosis (AIS), is the most common non-surgical approach used to prevent curvature progression. The study aims to a...

    Authors: Vitaliy Trofimchuk, Aliya Atepileva, Dilnoza Karibzhanova, Alexandr Kriklivyy and Stanislav Danilenko
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:464
  21. Hypermobility of the first ray is related to many foot problems. Existing methods to assess this condition have diverse advantages and disadvantages. The aims of this study were 1) to define the optimal cutoff...

    Authors: Jirawat Saengsin, Pichitchai Atthakomol, Nuttaya Pattamapaspong and Tanawat Vaseenon
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:463
  22. The distal tibiofibular syndesmosis is a key structure for the ankle joint’s stability and function, especially when the body is weight-bearing. Recent literature indicates that weight-bearing radiographs demo...

    Authors: Javid Mohammadzadeh Azarabadi, Neveen Shalalfa, Kemal Gökkuş and Saleh Shalalfa
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:461
  23. The study's objectives were to assess the sarcopenia prevalence in hip fracture patients admitted to a North African (Egyptian) level one specialized trauma unit and to evaluate factors associated with sarcope...

    Authors: Dalia G Mahran, Ahmed A. Khalifa, Abdelhafeez Hamdi Abdelhafeez and Osama Farouk
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:459
  24. Posterior Lumbar Interbody Fusion (PLIF) is a surgical procedure in which stabilization of spinal segments is achieved by inserting interbody cages filled with bone graft. Positron Emission Tomography (PET) is...

    Authors: Marloes J. M. Peters, Roel Wierts, Elisabeth M. C. Jutten, Wouter A. M. Broos, Mariel P. ter Laak and Paul C. Willems
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:458
  25. Total knee arthroplasty (TKA) has significant perioperative blood loss and a high transfusion rate. Tranexamic acid (TXA) has widely recognized hemostatic efficacy in TKA. Hemocoagulase Agkistrodon (HCA) enhan...

    Authors: Yucan Ju, Huansheng Liu, Wenyu Jiang, Qiang Huang, Zongke Zhou and Fuxing Pei
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:457
  26. Postmenopausal osteoporosis (PMOP) is a bone disorder in postmenopausal women and a significant risk factor for fragility fractures. This study aims to explore the role of miR-106a-5p in the pathogenesis of PM...

    Authors: Xiangjie Liu, Xiaogang Zhang and Meini Cen
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:456
  27. This prospective randomized controlled study explores the effectiveness of two exsanguination techniques in total knee arthroplasty (TKA), comparing Esmarch bandages and simple leg elevation concerning surgica...

    Authors: Sirisak Chaitantipongse, Natthapong Hongku and Satit Thiengwittayaporn
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:455
  28. The changes in the mechanical environment of local nerves after peripheral nerve injury (PNI) can cause a series of mechanical electrochemical signal reactions that affect the process of nerve regeneration and...

    Authors: Yue Xu, Na Rentuya, Tianyuan Yu, Jiawang Yan, Hongzheng Zhang, Yingqi Zhang, Hanyu Zhang, Jiawei Sun and Jiayue Liu
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:454
  29. A literature review and meta-analysis were conducted on studies comparing posterior fixation and fusion (PFF) and combined anterior and posterior fixation and fusion (CAPFF) for type B and C thoracolumbar inju...

    Authors: Vincent L. Mkochi, Hari Sharma, Alexis G. Gonazlez and Hao-Hua Wu
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:453
  30. The Double Bundle Medial Patellofemoral Ligament (MPFL) Reconstruction is a reliable technique for patellar instability. Clinical studies have shown its effectiveness and reliability in minimum 5-year follow-u...

    Authors: Jun-Ying Wu, Tian-Xin Chen, Yan Li and Lei Zhang
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:452
  31. Lateral extra-articular tenodesis (LET) is a surgical technique that can be used in conjunction with anterior cruciate ligament reconstruction (ACLR), improving rotational stability and reducing the risk of an...

    Authors: Jan Zabrzyński, Jakub Erdmann, Maria Zabrzyńska, Łukasz Łapaj, Shahbaz S. Malik and Adam Kwapisz
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:451
  32. Parthenolide (PTL) is a natural sesquiterpene lactone that possesses significant effects on stimulating osteoblast differentiation. The present study focused on the potential of PTL in the treatment of glucoco...

    Authors: Yanling Feng and Zhaoyang Li
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:450
  33. Comminuted fractures, characterized by multiple bone fragments, present significant challenges in orthopedic surgery. Effective treatment often requires augmentation techniques to enhance fixation stability an...

    Authors: S-Sina Mohammadi, Sunjeev S. Phull, B. Sonny Bal and Mark R. Towler
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:449
  34. Remote ischaemic conditioning (RIC) involves the use of controlled and transient ischemia and reperfusion cycles, commonly of the upper or lower limb, to mitigate cellular damage from ischaemic events. Studies...

    Authors: Alison Buck, Tao Wang, Sheharyar S. Baig, Arshad Majid and Ali N. Ali
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:448
  35. Phalangeal neck fractures (PNFs) are predominantly observed in the pediatric population. This study aims to investigate surgical outcomes and complications of PNF in children less than 3 years of age.

    Authors: Yang Liu, Hang Chen, Yunlan Xu and Bingqiang Han
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:447
  36. Lumbar fusion surgery is a common procedure for treating various degenerative spinal conditions. However, the incidence of proximal adjacent segment degeneration (PASD) remains a concern. This study aimed to i...

    Authors: Feng Qin, Weiqiang Fan, Lili Ren, Qi Chen, Xiaoxiao Chen and Wenjun Liu
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:446
  37. Ejiao, a traditional Chinese medicinal product derived from donkey’s hide, has long been used to promote blood formation and treat various ailments. Recently, growing pharmacological evidence has suggested tha...

    Authors: Yuanzhong Wang, Guiju Chen, Xia Ji, Sok Kuan Wong, Sophia Ogechi Ekeuku and Kok-Yong Chin
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:445
  38. Spinal stenosis is a common disease in clinical practice, and drug use is one of its potential predisposing factors. Alendronate, a widely used clinical drug for osteoporosis treatment, has the potential to tr...

    Authors: Nan Yang, Jingkai Di, Xiang Han, Wei Zhang, Xinliang Cui and Haoyu Feng
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:444
  39. To investigate the causal correlation and toxicological mechanisms of omeprazole in intervertebral disc degeneration (IVDD), alongside a particular emphasis on Caspase-3 (CASP3) mediated apoptosis of nucleus p...

    Authors: Yuchao Jia, Haifan Zhao, Shengbo Huang and Baoshan Xu
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:443
  40. Patellar component design in total knee arthroplasty (TKA) can influence patellofemoral kinematics and clinical outcomes. The medialized dome design (MDD) aligns the patella apex more medially, while the anato...

    Authors: Sina Hajiaghajani, Omid Bahrami, Mohammadhossein Hefzosseheh, Maryam Alaei, Amir Mehrvar and Mohammad Poursalehian
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:442
  41. Osteoarthritis (OA) is an age-related progressive degenerative disorder characterized by cartilage extracellular matrix degradation and inflammation. In this study, we explored the function and mechanism of ac...

    Authors: Yong Gao, Ke Wang, Chao Shi, Yang Gao and De-Qian Kong
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:441
  42. Surgical errors of orthopedics robotic are influenced by a multitude of factors. This study aims to investigate the impact of non-navigational errors on the accuracy of pedicle screw placement in orthopedic su...

    Authors: Yongkang Yang, Yishi Jia, Chang Liu, Liang Li and Boyao Wang
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:440
  43. Osteoarthritis (OA) affects weight-bearing joints, such as hips and knees, and its prevalence is rising due to factors like obesity and aging. Muscle atrophy, exacerbated by aging and surgery, increases the ri...

    Authors: Yashar Khani, Ali Salmani, Mohammad Elahi, Iman Elahi Vahed, Elias Sadooghi Rad, Alireza Bahrami Samani, Shaghayegh Karami, Mohammad Nouroozi and Amir Mehrvar
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:439
  44. This study aimed to enhance the rehabilitation process for patients with unstable pelvic Tile C fractures resulting from polytrauma by integrating mechanotherapy using the Hocoma Lokomat robotic device with co...

    Authors: Khan Akhtar Ali, LingXiao He, Weikai Zhang, Chengyan Xia, Hui Huang and Hui Huang Emails
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:438
  45. In this cadaveric study, we aimed to assess the effects of distraction at the anterior end of the cervical facet joints (CFJ), achieved via a posterior cervical approach (PCA), on intervertebral neural foramin...

    Authors: Amro Al-Habib, Sami AlEissa and Ayman Al-Jazaeri
    Citation: Journal of Orthopaedic Surgery and Research 2025 20:437

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